Antagonist IVF Protocol Sample Calendar

Antagonist IVF Protocol Sample Calendar

In Vitro Fertilization Protocol Using Ganirelix or Cetrotide

Ganirelix (Antagonist) IVF Protocol Calendar

USING BIRTH CONTROL PILLS

Sunday Monday Tuesday Wednesday Thursday Friday Saturday
1
Last birth control pill (of about 17 pills)
2
Nothing
3
Nothing
4
Nothing
5
Nothing
6
Baseline blood and ultrasound
Start stimulation shots (FSH) in evening
7
Stimulation day 2
8
Stimulation day 3
9
Stimulation day 4
10
Stimulation day 5
Blood and ultrasound
11
Stimulation day 6
Start of Ganirelix
12
Stimulation day 7
Blood and ultrasound
Ganirelix
13
Stimulation day 8
Ganirelix
14
Stimulation day 9
Blood and ultrasound – follicles now are ready
“Trigger shot” at night
15 16
Egg Retrieval Procedure
17
Fertilization check in morning
Start progesterone
18 19
Embryo Transfer Procedure
Day 3 transfer of cleavage stage embryos
20 21
Embryo Transfer Procedure
Day 5 transfer of blastocyst stage embryos
22 23 24 25 26 27 28
29 30
Blood pregnancy test

Key to antagonist IVF schedule:

Blood and ultrasound = blood test for IVF hormone values (estrogen levels in IVF stimulation are important) and transvaginal ultrasound to measure the follicle sizes in the ovaries. These visits usually take about 20-30 minutes in our offices and can be scheduled as early as 6:30AM.

Ganirelix = subcutaneous injection of a medication (GnRH antagonist). This drug is taken once daily starting on about day 6 of stimulation.

Stim = ovarian stimulation. Involves subcutaneous injection of a medication containing follicle stimulating hormone (FSH), which causes multiple follicles containing eggs to develop in the ovaries. Ovarian stimulation usually lasts about 8-11 days.

HCG injection = subcutaneous or intramuscular injection of a medication called HCG, which causes the eggs to complete the maturation process. This is taken only once in the cycle.

Progesterone = vaginal cream or suppositories or intramuscular injection of a medication (female hormone) called progesterone. This drug helps to prepare a receptive uterine lining for embryo implantation.

Egg retrieval procedure = procedure to get eggs from the ovaries

Embryo transfer procedure = procedure to put embryos in the uterus

  • The example above is a fairly typical IVF cycle.
  • Most patients will need 4 visits for monitoring the stimulation (shown as “Blood and Ultrasound” on the calendar) before the HCG trigger shot.
  • Some women will need only 3 monitoring visits and some may require 5 or even 6 visits.
  • It depends on the woman’s response to the ovarian stimulating medications.
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